The newest Kentucky Fried Chicken is at the end of the Route de Vienne. It's best gotten to by car, but you can also get there on the 12.
383 route de Vienne 69200 Vénissieux
I haven't been to this one yet. On the map it looks like it's right across from the Carré de Soie shopping center. You can get fairly close to there on the A line or the T3.
257 rue Léon Blum (Carré de Soie) 69100 Villeurbanne
There is also another one:
Rue du Commerce 69700 GIVORS